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Powassan Antibodies, IgG, IgM

Test: Powassan Antibodies, IgG, IgM


Testing for:
Powassan Virus
Sample Type:
Whole Blood, Plasma, Serum
Test Code/s:
  • Uses

    Indirect Testing: Powassan Serology Test (Serology)

    Measurement of patient’s antibody response to the virus

    • IgG and IgM antibodies specific for Powassan detected
    • Test is useful for determining stage of infection including chronic disease


    EIA/IFA (Serology):

    The EIA measures IgG and IgM antibodies to members of the tick-borne encephalitis complex (TBE-C). Due to the homology between these viruses, antibodies that cross-react with the TBE virus substrate in the EIA kit are found in samples from patients exposed to any member of the complex to a varying degree. If the sample is positive using specific criteria set by Coppe Laboratories, confirmation is done by IFA. IFA is performed by incubating patient samples on slides with virus-infected cells and then staining with fluorescein-labeled anti-human antibodies. Positive staining is visualized with a fluorescent microscope.