How Coppe Laboratories helps patients and families
Getting the best treatment possible often depends upon determining the type of infection and reporting those results in a timely fashion. Better testing leads to better treatment choices which may improve quality of life.
Coppe Laboratories is a specialized diagnostic laboratory that provides laboratory tests with emphasis on the interaction between infection and immunity. Our scientists have a long standing history of studying viral and other infectious diseases and their impact on the immune response, and have extensive publications.
Our Specialized Tests
HHV-6 in Infertility
Human herpesvirus 6 (HHV-6) is suspected to be involved in several types of gestational complications, including miscarriage and premature birth. Studies have shown that HHV-6 can be found in 43% of women with unexplained infertility. The ability of an HHV-6 infection to disrupt the environment of the uterus and development of the unborn baby may result in infertility and pregnancy loss.
Coppe Laboratories’ offers the most sensitive method for detection of HHV-6 in uterine tissue samples. With the growing evidence of an association between HHV- 6 and infertility, we recommend testing all patients experiencing unexplained infertility, repeated implantation failures and multiple miscarriages.
A Guide to the Powassan Virus
The Powassan Guide is a primer on the Powassan virus.Download a copy of the Powassan Guide
Transmitted by the tick known to carry Lyme disease bacteria, the Powassan virus (POWV) is a member of the family of viruses that include such familiar names as Zika, West Nile, Yellow Fever, and Dengue Fever. Until now, only a few state laboratories and the Centers for Disease Control and Prevention (CDC) were testing for POWV. Coppe Laboratories is the first reference laboratory to provide the testing.
POWV symptoms bear similarities to Lyme disease symptoms. Fatigue, headache, and general flu-like symptoms are seen within 2–7 days of exposure. Sometimes high fevers can occur. The initial viremic stage is followed by 2–3 weeks of a symptom-free period. Encephalitis can develop. Because symptoms associated with POWV closely resemble those of Lyme disease, the virus may be overlooked – yet directly contribute to disease long term.
Coppe Laboratories performs both direct (PCR) and indirect (serology) testing for POWV. A blood test is all that is required. Test results are usually available in under 14 days.
Lyme Disease and Coinfection
Lyme Disease: How and What We are Looking For
Physicians are usually responsible for ordering testing for Lyme disease, but patients may also make an inquiry. When Lyme disease is suspected, testing occurs a few weeks after tick exposure. This is because Lyme panels test antibodies, which don’t appear in the blood until 4-6 weeks after the tick bite.
Lyme disease is spread by a tick bite which may go unnoticed or result only in a painless rash. Identifying the early signs and seeking treatment early reduces the severity of the disease and the duration of the symptoms.
The recommended testing for Lyme disease uses a two-step approach. The first blood test is a screening test that uses enzyme-linked immunoabsorbent assay (often called ELISA) to measure antibodies caused by the infection. If the result from this test is positive or indeterminate, a second, more specific blood test (on the same blood sample) is run to confirm the results.
Coppe Laboratories’ Lyme testing checks for the most important strains and species of the bacteria. Results are provided within five business days after the receipt of sample.
The most common arthropod-borne diseases found in the U.S. are carried by ticks and mosquitoes. Mosquitoes are responsible for more human deaths globally than all other animals combined! In most cases, the clinical symptoms of arthropod-borne illnesses are non-specific and can vary from mild to severe. As few signs and symptoms are specific to any one disease, differentiation by appropriate laboratory testing is critical when considering treatment options. Coppe Laboratories’ Arthropod-borne Disease Panel detects exposure to the agents responsible for > 98% of arthropod-borne illness in the U.S. The panel includes the following tests: Lyme Screen and Immunoblot, Powassan Virus IgG/IgM, West Nile Virus IgG/IgM, Babesia IgG, and Anaplasma IgG/IgM.